Why Does My Baby Make A Fuss?

my baby girls 4 months old now,and my husband and i went on a 1 hour trip to the beach side over the Christmas period wit my daughter.Now this was my babies first little holiday,and my husband and thought it would be a good way of going into 2011 like a family.As we get up the the next day my husbands parents come up,and stayed up there for the full 5 days.I understand she the first grandchild and te excited,but it made me mad,the whole time they where in my babies face ,picking her up all the time ,even when she was crying and i was trying to put her to bed and settle her.As soon as we got home shes forgoten her routine through out the day and at night,shes very unsettled.do you think its because of taking her out of the house?will she ever go back how she was?or im thinking something else is wrong, she growns all day and hard to settle ,every time i give her a bottle she squirms for about 15 Min's then settles, what wrong with her?help!